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A Model for Compression-Weakening Materials and the Elastic Fields due to Contractile Cells

机译:压缩 - 弱化材料模型和弹性场   到收缩细胞

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摘要

We construct a homogeneous, nonlinear elastic constitutive law, that modelsaspects of the mechanical behavior of inhomogeneous fibrin networks. Fibers insuch networks buckle when in compression. We model this as a loss of stiffnessin compression in the stress-strain relations of the homogeneous constitutivemodel. Problems that model a contracting biological cell in a finite matrix aresolved. It is found that matrix displacements and stresses induced by cellcontraction decay slower (with distance from the cell) in a compressionweakening material, than linear elasticity would predict. This points toward amechanism for long-range cell mechanosensing. In contrast, an expanding cellwould induce displacements that decay faster than in a linear elastic matrix.
机译:我们构建了一个均匀的,非线性的弹性本构律,该模型对非均质纤维蛋白网络的力学行为进行了建模。这种网络中的光纤在压缩时会弯曲。我们将此模型建模为均质本构模型的应力-应变关系中的压缩刚度损失。解决了在有限矩阵中建模生物收缩细胞的问题。结果发现,在压缩弱化材料中,由细胞收缩引起的基体位移和应力衰减(随细胞距离的变化)比线性弹性所预测的要慢。这指向用于长距离细胞机械传感的机制。相反,膨胀的细胞将引起比线性弹性矩阵更快地衰减的位移。

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